Genetics loads the gun. Lifestyle pulls the trigger. At 24byMe, we measure both — your inherited genetic risk variants AND your current epigenetic age (DNA methylation). This tells us not just what you’re predisposed to, but how your lifestyle is currently shaping your biological age.
Genetic medicine identifies inherited risk variants that predispose you to certain conditions — including ApoE ε4 (cardiovascular and Alzheimer’s risk), TCF7L2 (type 2 diabetes), FTO (obesity predisposition), and PPARγ (insulin sensitivity).
Epigenetic medicine goes a step further. It measures how your lifestyle and environment are modifying your gene expression through DNA methylation patterns. The DNA-methylation epigenetic clock is a validated test that calculates your biological age based on methylation at specific sites across your genome.
The gap between your biological age and chronological age tells a powerful story. A biological age younger than your chronological age suggests your lifestyle is protecting you. An older biological age is a warning sign — and an opportunity.
DNA-methylation epigenetic age predicts morbidity and mortality better than chronological age
Epigenetic age can be slowed or partially reversed through lifestyle intervention
ApoE ε4 carriers have elevated CVD and Alzheimer’s risk — but lifestyle powerfully modifies the outcome
Our assessments reveal what you’re working with — and what you can change.
| Assessment | What It Measures | How It Guides Treatment |
|---|---|---|
| Family History Mapping (all Precision Health Insights tiers) | Structured family history across 3 generations | Identifies patterns; guides screening frequency |
| ApoE Genotyping (Precision Health: Longevity) | ApoE ε2/ε3/ε4 variants | Informs cardiovascular and cognitive health protocols |
| DNA-methylation epigenetic age (Precision Health: Longevity) | Epigenetic biological age | Baseline for tracking lifestyle intervention effectiveness |
| Risk Modelling (Precision Health: Longevity) | Combined genetic + epigenetic + metabolic risk | Determines program intensity and monitoring frequency |
DNA-methylation epigenetic age tells you how fast you're aging at a cellular level — and whether your interventions are working.
We don't just tell you your risk. We prescribe specific lifestyle interventions that modify the expression of your risk genes.
Repeat epigenetic testing at intervals shows objective proof that your lifestyle is slowing or reversing your biological age.
Dr. Viral Bhatt, MD | Corporate HQ — Vile Parle, Mumbai · Sindhu Bhavan Road, Ahmedabad | Online across India